NMN Food (nicotinamide mononucleotide) is among the most studied and researched substances for slowing aging.
NMN (nicotinamide mononucleotide) is a chemical that is naturally present in our system.
NMN (nicotinamide mononucleotide) can be regarded as a precursor for NAD+. NAD+ is a vital molecule found in all the cells in our body.
NAD+ is a chemical that various proteins and enzymes must use to fulfill their functions.
For instance, NAD+ is required to properly maintain and repair our epigenome and DNA (by enzymes such as sirtuins or PARPs).
What are the consequences of NMN Food?
1. NMN boosts the energy levels
Most of the time, people say they are more energetic after they take NMN Food.
For a boost in energy, you must get a sufficient dose.
Certain people have already experienced the effects of 500 mg of NMN Food. However, others require a minimum of 500 mg.
Studies have shown that the administration of NMN Food. enhances stamina and endurance in old mice by up to 80 percent. [1][2]
2. NMN enhances memory
Most people who utilize NMN Food. notice improvements in their cognitive performance, making people feel sharper or in their ability to focus.
Some studies show that NMN benefits brain functioning, increasing cognition and blood flow in mice's brains. [3]
3. NMN & healthier blood vessels
Studies have shown that NMN revitalizes the blood vessels of old age. NMN (nicotinamide mononucleotide) significantly enhances, for instance, vascular elasticity in elderly animals.
Additionally, mitochondria in the cells of blood vessels (endothelial cells) remain healthier when NMN is used. Mitochondria are the powerhouses of cells. [4]
4. NMN increases metabolism
This is crucial as the metabolism decreases dramatically and can increase the chance of developing many illnesses.
Research suggests that NMN Food can lower insulin resistance, enhance the lipid profile of plasma, help reduce weight gain associated with aging and increase physical exercise.[5][6][7][8]
5. NMN enhances decline associated with aging in older organisms
The following things decrease eyesight, stamina, energy levels, bone density, and immunity as we age. All of these are improved as per studies on older mice.[9][10]
6. NMN improves fertility
Certain people who take NMN Food claim to experience an increase in their libido.
Biotech companies have found that NMN and NMN derivatives could make old animals more fertile.
Research has shown that NMN Food improves fertilization. Find out more information on nmn and fertility.[11]
7. NMN helps improve the health of stem cells
As we age, our stem cells diminish in number, and stem cells tend to become deficient. This can lead to aging because stem cells create new cells and help maintain our tissues. Different studies demonstrate that NMN or increasing NAD levels may improve the health of stem cells and self-renewal.[12][13][14][15]
8. NMN repairs DNA damage
NMN assists cells in repairing damage to their DNA. DNA damage is among the reasons that we become older.
Mice who received NMN had significantly lower DNA damage (as measured by alpha H2AX, a biomarker of DNA damage):
In one study, mice were irradiated in a manner that generally causes massive amounts of DNA damage, killing large numbers of red blood cells. However, when mice received NMN and received it, they showed significantly greater levels of red blood cells when compared to mice that were not given NMN (as determined by the hemoglobin levels).
Numerous other studies have shown the beneficial effects of NMN in reducing aging and sometimes even reversing specific age-related conditions in older animals to a more youthful state.[16]
Find out more about RevGenetics' Advanced NMN here.
Follow the NMN blog to keep up-to-date with news from NMN Food!
Synergy is a key ingredient when it comes to anti-aging supplements
In the end, many anti-aging products are based on outdated theories and don't contain any limited research to support their claims.
Additionally, they don't contain chemicals proven to influence aging processes (the " hallmarks of aging").
An effective anti-aging product has scientifically proven ingredients and affects the aging process. These supplements also allow them to offer an additional benefit which is synergy.
Ultimately, it is a complicated process caused by many different mechanisms, like epigenetic disorder, mitochondrial dysfunction, and protein accumulation.
Suppose you're using an anti-aging product focused on "improving mitochondrial health." In this case, you do not take care of other critical mechanisms related to aging-related to epigenetic dysregulation or protein build-up.
So, although it may boost mitochondrial health, this supplement is unlikely to impact the length of life as it only addresses one aspect of aging.
Therefore, an effective anti-aging supplement synergistically must-have ingredients that affect different age-related mechanisms.
For instance, alpha-ketoglutarate (AKG) can help maintain the epigenome and improve mitochondrial health. AKG may be used with other compounds that enhance mitochondrial health, such as fisetin and malate, and those that enhance the epigenome, such as the NMN and Glycine.
However, dealing with the mitochondrial epigenome is aging, and the epigenome needs to be more. It is also necessary to address several other aging-related mechanisms, such as the accumulation of proteins and DNA damage.
Additional anti-aging compounds must be included, for instance, lithium (which helps to reduce the levels of protein through stimulating autophagy, which is the process of digestion) or Acetylglucosamine, which also helps to decrease the accumulation of proteins and magnesium, which can aid in stabilizing the DNA to achieve this.
Therefore, the best anti-aging supplement consists of more than just a couple of products concentrating on one aging mechanism (like mitochondrial health or NAD and metabolism). It also contains substances that can synergistically affect many different aging pathways.
RevGenetics offers some of the essential supplements you'll ever need.
Check us out to learn more about our other supplements, such as Best Resveratrol Supplement and NMN Food.
References:
- https://news.mit.edu/2018/study-suggests-method-boost-growth-blood-vessels-muscle-0322
- https://www.jsams.org/article/S1440-2440(17)31610-9/fulltext
- https://www.sciencedirect.com/science/article/pii/S221323171930240X#bib11
- https://www.researchsquare.com/article/rs-1802944/latest.pdf
- https://pubmed.ncbi.nlm.nih.gov/28068222/
- https://pubmed.ncbi.nlm.nih.gov/27594836/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204926/
- https://www.nature.com/articles/s41598-017-14866-z
- https://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30495-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413116304958%3Fshowall%3Dtrue
- https://pubmed.ncbi.nlm.nih.gov/28068222/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063679/
- https://www.nature.com/articles/s41419-019-1569-2
- https://onlinelibrary.wiley.com/doi/full/10.1111/acel.12935
- https://pubmed.ncbi.nlm.nih.gov/24811750/
- https://www.embopress.org/doi/full/10.15252/embj.201488969?cookieSet=1
- https://www.sciencedirect.com/science/article/pii/S0891584922008978
